Gene expression pattern and progression of embryogenesis in the immediate post-implantation period of mouse development

被引：96

作者：

Pfister, Sabine

Steiner, Kirsten A.

Tam, Patrick P. L.

机构：

[1] Univ Sydney, Childrens Med Res Inst, Embryol Unit, Wentworthville, NSW 2145, Australia

[2] Univ Sydney, Fac Med, Wentworthville, NSW 2145, Australia

来源：

GENE EXPRESSION PATTERNS | 2007年 / 7卷 / 05期

基金：

英国医学研究理事会;

关键词：

gene expression; tissue patterning; signalling; embryogenesis; post-implantation; mouse;

D O I：

10.1016/j.modgep.2007.01.005

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

During development of the mouse conceptus from implantation to the early gastrula stage, a multitude of genes encoding structural proteins, transcription factors and components of signalling pathways are expressed in the extraembryonic and embryonic tissues derived from the trophectoderm and the inner cell mass. Some genes are expressed widely in the extraembryonic ectoderm, the visceral endoderm or the epiblast, while others display more restricted expression domains in these tissues or are expressed upon the specification of the germ layers at gastrulation. Overall, the developmental changes in gene expression mirror key events of embryogenesis, and reveal the regionalization of signalling activity and the emergence of tissue patterning. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：558 / 573

页数：16

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[91] Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst [J].