Gene expression pattern and progression of embryogenesis in the immediate post-implantation period of mouse development

被引:96
作者
Pfister, Sabine
Steiner, Kirsten A.
Tam, Patrick P. L.
机构
[1] Univ Sydney, Childrens Med Res Inst, Embryol Unit, Wentworthville, NSW 2145, Australia
[2] Univ Sydney, Fac Med, Wentworthville, NSW 2145, Australia
基金
英国医学研究理事会;
关键词
gene expression; tissue patterning; signalling; embryogenesis; post-implantation; mouse;
D O I
10.1016/j.modgep.2007.01.005
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
During development of the mouse conceptus from implantation to the early gastrula stage, a multitude of genes encoding structural proteins, transcription factors and components of signalling pathways are expressed in the extraembryonic and embryonic tissues derived from the trophectoderm and the inner cell mass. Some genes are expressed widely in the extraembryonic ectoderm, the visceral endoderm or the epiblast, while others display more restricted expression domains in these tissues or are expressed upon the specification of the germ layers at gastrulation. Overall, the developmental changes in gene expression mirror key events of embryogenesis, and reveal the regionalization of signalling activity and the emergence of tissue patterning. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:558 / 573
页数:16
相关论文
共 109 条
[11]   Anterior patterning in mouse [J].
Beddington, RSP ;
Robertson, EJ .
TRENDS IN GENETICS, 1998, 14 (07) :277-284
[12]   The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4 [J].
Ben-Haim, Nadav ;
Lu, Cindy ;
Guzman-Ayala, Marcela ;
Pescatore, Luca ;
Mesnard, Daniel ;
Bischofberger, Mirko ;
Naef, Felix ;
Robertson, Elizabeth J. ;
Constam, Daniel B. .
DEVELOPMENTAL CELL, 2006, 11 (03) :313-323
[13]   Murine cerberus homologue mCer-1: A candidate anterior patterning molecule [J].
Biben, C ;
Stanley, E ;
Fabri, L ;
Kotecha, S ;
Rhinn, M ;
Drinkwater, C ;
Lah, M ;
Wang, CC ;
Nash, A ;
Hilton, D ;
Ang, SL ;
Mohun, T ;
Harvey, RP .
DEVELOPMENTAL BIOLOGY, 1998, 194 (02) :135-151
[14]   Nodal signalling in the epiblast patterns the early mouse embryo [J].
Brennan, J ;
Lu, CC ;
Norris, DP ;
Rodriguez, TA ;
Beddington, RSP ;
Robertson, EJ .
NATURE, 2001, 411 (6840) :965-969
[15]   Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo [J].
Camus, Anne ;
Perea-Gomez, Aitana ;
Moreau, Anne ;
Collignon, Jerome .
DEVELOPMENTAL BIOLOGY, 2006, 295 (02) :743-755
[16]   Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells [J].
Chambers, I ;
Colby, D ;
Robertson, M ;
Nichols, J ;
Lee, S ;
Tweedie, S ;
Smith, A .
CELL, 2003, 113 (05) :643-655
[17]   Disruption of early proximodistal patterning and AVE formation in Apc mutants [J].
Chazaud, Claire ;
Rossant, Janet .
DEVELOPMENT, 2006, 133 (17) :3379-3387
[18]   Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway [J].
Chazaud, Claire ;
Yamanaka, Yojiro ;
Pawson, Tony ;
Rossant, Janet .
DEVELOPMENTAL CELL, 2006, 10 (05) :615-624
[19]   Expression of the T-box gene Eomesodermin during early mouse development [J].
Ciruna, BG ;
Rossant, J .
MECHANISMS OF DEVELOPMENT, 1999, 81 (1-2) :199-203
[20]   SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis [J].
Constam, DB ;
Calfon, M ;
Robertson, JJ .
JOURNAL OF CELL BIOLOGY, 1996, 134 (01) :181-191