Theoretical methods for the description of the solvent effect in biomolecular systems

被引：524

作者：

Orozco, M

Luque, FJ

机构：

[1] Univ Barcelona, Fac Quim, Dept Bioquim & Biol Mol, E-08028 Barcelona, Spain

[2] Univ Barcelona, Fac Farm, Dept Fisicoquim, E-08028 Barcelona, Spain

来源：

CHEMICAL REVIEWS | 2000年 / 100卷 / 11期

关键词：

D O I：

10.1021/cr990052a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Within the past few years, theoretical chemists have realized that a detailed understanding of chemical or biochemical systems is impossible without an accurate description of their solvent effects. This review of summarizes the most important characteristics of the different approaches, emphasizing their strengths and weaknesses.

引用

页码：4187 / 4225

页数：39

共 922 条

[71]

2-W

[72]

Barril X, 1998, PROTEINS, V32, P67, DOI 10.1002/(SICI)1097-0134(19980701)32:1<67::AID-PROT8>3.0.CO

[73]

2-B

[74] The lubricant of life: A proposal that solvent water promotes extremely fast conformational fluctuations in mobile heteropolypeptide structure [J].