Recent developments in the encoding and deconvolution of combinatorial libraries

被引:30
作者
Barnes, C [1 ]
Balasubramanian, S [1 ]
机构
[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1016/S1367-5931(00)00098-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Value of molecular libraries generated by combinatorial methods is largely dependent on the ease and ability to deconvolute or decode the structure of compounds of interest after screening the library. Following the introduction of promising concepts in the early 1990s, there has been considerable progress in the development and refinement of methodologies to address this issue.
引用
收藏
页码:346 / 350
页数:5
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