ATP-dependent chromatin remodeling is performed by multi-subunit protein complexes. Over the last years, the identity of these factors has been unveiled in yeast and many parallels have been drawn with animal and plant systems, indicating that sophisticated chromatin transactions evolved prior to their divergence. Here we review current knowledge pertaining to the molecular mode of action of ATP-dependent chromatin remodeling, from single molecule studies to genome-wide genetic and proteomic studies. We focus on the budding yeast versions of SWI/SNF, RSC, DDMI, ISWI, CHD1, INO80 and SWR1. (c) 2007 Elsevier B.V. All rights reserved.
机构:Univ Utah, Sch Med, Howard Hughes Med Inst, Huntsman Canc Inst, Salt Lake City, UT 84108 USA
Angus-Hill, ML
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Schlichter, A
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Schlichter, A
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Roberts, D
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Roberts, D
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Erdjument-Bromage, H
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Erdjument-Bromage, H
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Tempst, P
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Tempst, P
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Cairns, BR
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机构:Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada
Baetz, KK
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Krogan, NJ
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Krogan, NJ
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Emili, A
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Emili, A
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Greenblatt, J
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Greenblatt, J
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Hieter, P
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机构:Univ Utah, Sch Med, Howard Hughes Med Inst, Huntsman Canc Inst, Salt Lake City, UT 84108 USA
Angus-Hill, ML
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Schlichter, A
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Schlichter, A
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Roberts, D
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Roberts, D
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Erdjument-Bromage, H
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Tempst, P
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Tempst, P
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Cairns, BR
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Univ Utah, Sch Med, Howard Hughes Med Inst, Huntsman Canc Inst, Salt Lake City, UT 84108 USAUniv Utah, Sch Med, Howard Hughes Med Inst, Huntsman Canc Inst, Salt Lake City, UT 84108 USA
机构:Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada
Baetz, KK
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Krogan, NJ
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机构:Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada
Krogan, NJ
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Emili, A
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机构:Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada
Emili, A
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Greenblatt, J
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机构:Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada
Greenblatt, J
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Hieter, P
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Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaUniv British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada