Evaluation of the epidemiologic utility of secondary typing methods for differentiation of Mycobacterium tuberculosis isolates

被引:72
作者
Kwara, A
Schiro, R
Cowan, LS
Hyslop, NE
Wiser, MF
Harrison, SR
Kissinger, P
Diem, L
Crawford, JT
机构
[1] Tulane Univ, Sch Publ Hlth & Trop Med, Dept Trop Med, New Orleans, LA 70112 USA
[2] Tulane Univ, Sch Publ Hlth & Trop Med, Dept Epidemiol, New Orleans, LA 70112 USA
[3] Tulane Univ, Hlth Sci Ctr, Sect Adult Infect Dis, New Orleans, LA 70112 USA
[4] Louisiana Dept Hlth & Hosp, Off Publ Hlth, New Orleans, LA 70112 USA
[5] Ctr Dis Control & Prevent, Div AIDS STD & TB Lab Res, Natl Ctr Infect Dis, Atlanta, GA 30333 USA
关键词
D O I
10.1128/JCM.41.6.2683-2685.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Spoligotyping and mycobacterial interspersed repetitive unit-variable-number tandem repeat analysis (MIRU-VNTR) were evaluated for the ability to differentiate 64 Mycobacterium tuberculosis isolates from 10 IS6110-defined clusters. MIRU-VNTR performed slightly better than spoligotyping in reducing the number of clustered isolates and the sizes of the clusters. All epidemiologically related isolates remained clustered by MIRU-VNTR but not by spoligotyping.
引用
收藏
页码:2683 / 2685
页数:3
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