Copper-in-Charcoal-Catalyzed, Tandem One-Pot Diazo Transfer-Click Reactions

被引：61

作者：

Lee, Ching-Tien ^{[1
]}

Huang, Shenlin ^{[1
]}

Lipshutz, Bruce H. ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2009年 / 351卷 / 18期

关键词：

click chemistry; copper-in-charcoal; diazo transfer; heterogeneous catalysis; AZIDES; 1,2,3-TRIAZOLES; CYCLOADDITION;

D O I：

10.1002/adsc.200900604

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Copper-in-charcoal (Cu/C) is an effective heterogeneous catalyst for tandem diazo transfer/click reactions. In the presence of Cu/C, various azides can be generated in situ from the corresponding amines, and subsequently undergo [3+2]cycloaddition with terminal alkynes to afford tri-azoles in good yields. The catalyst is also easily recycled.

引用

页码：3139 / 3142

页数：4

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