Chemokines and HIV-1 second receptors: The therapeutic connection

被引：103

作者：

Cairns, JS

D'Souza, MP

机构：

[1] NIAID, Targeted Intervent Branch, Div Aids, Bethesda, MD 20892 USA

[2] NIAID, Pathogenesis & Basic Res Branch, Div Aids, Bethesda, MD 20892 USA

来源：

NATURE MEDICINE | 1998年 / 4卷 / 05期

关键词：

D O I：

10.1038/nm0598-563

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The discovery that HIV requires a chemokine co-receptor to invade host cells has prompted many investigations into therapeutic strategies that target these receptors in an attempt to block HIV entry. In this review, Scott Cairns and Patricia D'Souza discuss these potentially powerful approaches and how they complement existing antiretroviral drug therapy.

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收藏

页码：563 / 568

页数：6

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