New diterpenoids from the marine mangrove Bruguiera gymnorrhiza

被引：32

作者：

Han, L

Huang, XS

Sattler, I ^{[1
]}

Dahse, HM

Fu, HZ

Lin, WH

Grabley, S

机构：

[1] Peking Univ, Natl Res Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

[2] Hans Knoell Inst Nat Prod Res, D-07745 Jena, Germany

来源：

JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 09期

关键词：

D O I：

10.1021/np040062t

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical investigation of the stem of Bruguiera gymnorrhiza yielded three new ent-kaurane diterpenoids (1, 2, and 3) and one new ent-beyerane diterpenoid (4) together with nine known ent-kaurane diterpenoids. All structures and the relative stereochemistry of the new compounds were determined by NMR spectroscopic studies. The absolute stereochemistry of 4 was determined by CD data. Some of the compounds showed moderate cytotoxic properties.

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页码：1620 / 1623

页数：4

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