Bubble nucleation and cooperativity in DNA melting

被引：103

作者：

Ares, S ^{[1
]}

Voulgarakis, NK

Rasmussen, KO

Bishop, AR

机构：

[1] Los Alamos Natl Lab, Div Theoret, Los Alamos, NM 87545 USA

[2] Los Alamos Natl Lab, Ctr Nonlinear Studies, Los Alamos, NM 87545 USA

[3] Univ Carlos III Madrid, GISC, Madrid 28911, Spain

[4] Univ Carlos III Madrid, Dept Matemat, Madrid 28911, Spain

[5] Univ Crete, Dept Phys, Iraklion 71003, Crete, Greece

[6] Fdn Res & Technol Hellas, Iraklion 71003, Crete, Greece

来源：

PHYSICAL REVIEW LETTERS | 2005年 / 94卷 / 03期

关键词：

D O I：

10.1103/PhysRevLett.94.035504

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The onset of intermediate states (denaturation bubbles) and their role during the melting transition of DNA are studied using the Peyrard-Bishop-Dauxois model by Monte Carlo simulations with no adjustable parameters. Comparison is made with previously published experimental results finding excellent agreement. Melting curves, critical DNA segment length for stability of bubbles, and the possibility of a two-state transition are studied.

引用

页数：4

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