Image guidance for precise conformal radiotherapy

被引:427
作者
Mackie, TR
Kapatoes, J
Ruchala, K
Lu, WG
Wu, C
Olivera, G
Forrest, L
Tome, W
Welsh, J
Jeraj, R
Harari, P
Reckwerdt, P
Paliwal, B
Ritter, M
Keller, H
Fowler, J
Mehta, M
机构
[1] TomoTherapy Inc, Madison, WI USA
[2] Univ Wisconsin, Coll Vet Med, Madison, WI USA
[3] Univ Wisconsin, Sch Med, Dept Med Phys, Madison, WI USA
[4] Univ Wisconsin, Sch Med, Dept Human Oncol, Madison, WI USA
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2003年 / 56卷 / 01期
关键词
D O I
10.1016/S0360-3016(03)00090-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: To review the state of the art in image-guided precision conformal radiotherapy and to describe how helical tomotherapy compares with the image-guided practices being developed for conventional radiotherapy. Methods and Materials: Image guidance is beginning to be the fundamental basis for radiotherapy planning, delivery, and verification. Radiotherapy planning requires more precision in the extension and localization of disease. When greater precision is not possible, conformal avoidance methodology may be indicated whereby the margin of disease extension is generous, except where sensitive normal tissues exist. Radiotherapy delivery requires better precision in the definition of treatment volume, on a daily basis if necessary. Helical tomotherapy has been designed to use CT imaging technology to plan, deliver, and verify that the delivery has been carried out as planned. The image-guided processes of helical tomotherapy that enable this goal are described. Results: Examples of the results of helical tomotherapy processes for image-guided intensity-modulated radiotherapy are presented. These processes include megavoltage CT acquisition, automated segmentation of CT images, dose reconstruction using the CT image set, deformable registration of CT images, and reoptimization. Conclusion: Image-guided precision conformal radiotherapy can be used as a tool to treat the tumor yet spare critical structures. Helical tomotherapy has been designed from the ground up as an integrated image-guided intensity-modulated radiotherapy system and allows new verification processes based on megavoltage CT images to be implemented. (C) 2003 Elsevier Inc.
引用
收藏
页码:89 / 105
页数:17
相关论文
共 131 条
[1]   Portal imaging for evaluation of daily on-line setup errors and off-line organ motion during conformal irradiation of carcinoma of the prostate [J].
Alasti, H ;
Petric, MP ;
Catton, CN ;
Warde, PR .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2001, 49 (03) :869-884
[2]  
ALDRIDGE JS, 1999, TOMOGRAPHIC PATIENT
[3]   The registration of MR images using multiscale robust methods [J].
Alexander, ME ;
Somorjai, RL .
MAGNETIC RESONANCE IMAGING, 1996, 14 (05) :453-468
[4]   Prostate seed implant quality assessment using MR and CT image fusion [J].
Amdur, RJ ;
Gladstone, D ;
Leopold, KA ;
Harris, RD .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1999, 43 (01) :67-72
[5]  
[Anonymous], 1993, 50 ICRU
[6]   Magnetic resonance imaging system for three-dimensional conformal radiotherapy and its impact on gross tumor volume delineation of central nervous system tumors [J].
Aoyama, H ;
Shirato, H ;
Nishioka, T ;
Hashimoto, S ;
Tsuchiya, K ;
Kagei, K ;
Onimaru, R ;
Watanabe, Y ;
Miyasaka, K .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2001, 50 (03) :821-827
[7]   A FULLY-AUTOMATIC MULTIMODALITY IMAGE REGISTRATION ALGORITHM [J].
ARDEKANI, BA ;
BRAUN, M ;
HUTTON, BF ;
KANNO, I ;
IIDA, H .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1995, 19 (04) :615-623
[8]   Uncertainties in CT-based radiation therapy treatment planning associated with patient breathing [J].
Balter, JM ;
TenHaken, RK ;
Lawrence, TS ;
Lam, KL ;
Robertson, JM .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1996, 36 (01) :167-174
[9]   Daily targeting of intrahepatic tumors for radiotherapy [J].
Balter, JM ;
Brock, KK ;
Litzenberg, DW ;
McShan, DL ;
Lawrence, TS ;
Ten Haken, R ;
McGinn, CJ ;
Lam, KL ;
Dawson, LA .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2002, 52 (01) :266-271
[10]   ONLINE REPOSITIONING DURING TREATMENT OF THE PROSTATE - A STUDY OF POTENTIAL LIMITS AND GAINS [J].
BALTER, JM ;
CHEN, GTY ;
PELIZZARI, CA ;
KRISHNASAMY, S ;
RUBIN, S ;
VIJAYAKUMAR, S .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1993, 27 (01) :137-143