(-)-Frondosins A and D, HIV-inhibitory sesquiterpene hydroquinone derivatives from Euryspongia sp.

被引：55

作者：

Hallock, YF ^{[1
]}

Cardellina, JH ^{[1
]}

Boyd, MR ^{[1
]}

机构：

[1] NCI, Lab Drug Discovery Res & Dev, Dev Therapeut Program, Div Canc Treatment Diag & Ctr, Frederick, MD 21702 USA

来源：

NATURAL PRODUCT LETTERS | 1998年 / 11卷 / 02期

关键词：

HIV-inhibitory; sesquiterpene hydroquinone; Euryspongia; frondosin;

D O I：

10.1080/10575639808041212

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

(-)-Frondosins A and D, two sesquiterpene hydroquinone metabolites, were isolated and identified from the HIV-inhibitory organic extracts of the marine sponge Euryspongia sp. In contrast to the decalin rings found previously in bicyclic marine sesquiterpene quinones and quinols, (-)-frondosins A and D possess the less common bicyclo[5.4.0]undecane sesquiterpene ring system.

引用

页码：153 / 160

页数：8

共 24 条

[1]

Bergquist P. R., 1995, Memoirs of the Queensland Museum, V38, P1

[2] STUDIES IN SESQUITERPENES .34. STRUCTURE OF ALLOHIMACHALOL [J].