The emerging field of nanotube biotechnology

被引:684
作者
Martin, CR [1 ]
Kohli, P
机构
[1] Univ Florida, Dept Chem, Gainesville, FL 32611 USA
[2] Univ Florida, Ctr Res BioNano Interface, Gainesville, FL 32611 USA
基金
美国国家科学基金会;
关键词
D O I
10.1038/nrd988
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nanoparticles are being developed for a host of biomedical and biotechnological applications, including drug delivery, enzyme immobilization and DNA transfection. Spherical nanoparticles are typically used for such applications, which reflects the fact that spheres are easier to make than other shapes. Micro- and nanotubes - structures that resemble tiny drinking straws are alternatives that might offer advantages over spherical nanoparticles for some applications. This article discusses four approaches for making micro- and nanotubes, and reviews the current status of efforts to develop biomedical and biotechnological applications of these tubular structures.
引用
收藏
页码:29 / 37
页数:9
相关论文
共 56 条
[1]   Nanotubes from carbon [J].
Ajayan, PM .
CHEMICAL REVIEWS, 1999, 99 (07) :1787-1799
[2]  
AJAYAN PM, 1997, CARBON NANOTUBES PRE, pCH3
[3]   Bioelectrochemical single-walled carbon nanotubes [J].
Azamian, BR ;
Davis, JJ ;
Coleman, KS ;
Bagshaw, CB ;
Green, MLH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (43) :12664-12665
[4]   Logic circuits with carbon nanotube transistors [J].
Bachtold, A ;
Hadley, P ;
Nakanishi, T ;
Dekker, C .
SCIENCE, 2001, 294 (5545) :1317-1320
[5]  
Bard A. J., 2001, ELECTROCHEMICAL METH, P146
[6]   Resistive-pulse sensing - From microbes to molecules [J].
Bayley, H ;
Martin, CR .
CHEMICAL REVIEWS, 2000, 100 (07) :2575-2594
[7]   Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection [J].
Cao, YWC ;
Jin, RC ;
Mirkin, CA .
SCIENCE, 2002, 297 (5586) :1536-1540
[8]   Fabrication and characterization of concentric-tubular composite micro- and nanostructures using the template-synthesis method [J].
Cepak, VM ;
Hulteen, JC ;
Che, GL ;
Jirage, KB ;
Lakshmi, BB ;
Fisher, ER ;
Martin, CR .
JOURNAL OF MATERIALS RESEARCH, 1998, 13 (11) :3070-3080
[9]   Procedures for microencapsulation of enzymes, cells and genetically engineered microorganisms [J].
Chang, TMS ;
Prakash, S .
MOLECULAR BIOTECHNOLOGY, 2001, 17 (03) :249-260
[10]   Noncovalent sidewall functionalization of single-walled carbon nanotubes for protein immobilization [J].
Chen, RJ ;
Zhang, YG ;
Wang, DW ;
Dai, HJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (16) :3838-3839