The intrinsic function of a motor system -: from ion channels to networks and behavior

被引：89

作者：

Grillner, S ^{[1
]}

Cangiano, L ^{[1
]}

Hu, GY ^{[1
]}

Thompson, R ^{[1
]}

Hill, R ^{[1
]}

Wallén, P ^{[1
]}

机构：

[1] Karolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, Sweden

来源：

BRAIN RESEARCH | 2000年 / 886卷 / 1-2期

关键词：

locomotion; networks; ion channel; modulation; modeling; behavior;

D O I：

10.1016/S0006-8993(00)03088-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The forebrain, brainstem and spinal cord contribution to the control of locomotion is reviewed in this article. The lamprey is used as an experimental model since it allows a detailed cellular analysis of the neuronal network underlying locomotion. The focus is on cellular mechanisms that are important for the pattern generation, as well as different types of pre- and postsynaptic modulation. This experimental model is bridging the gap between the molecular and cellular level to the network and behavioral level. (C) 2000 Elsevier Science B.V. All rights reserved.

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收藏

页码：224 / 236

页数：13

相关论文

共 80 条

[1] PRESYNAPTIC GABA-A AND GABA-B RECEPTOR-MEDIATED PHASIC MODULATION IN AXONS OF SPINAL MOTOR INTERNEURONS [J].

ALFORD, S ;

CHRISTENSON, J ;

GRILLNER, S .

EUROPEAN JOURNAL OF NEUROSCIENCE, 1991, 3 (02) :107-117

[2]

ALFORD S, 1991, J NEUROSCI, V11, P3718

[3]

ANGIANO L, 2000, IN PRESS ACTA PHYS A, V19

[4] ACTIVITY-RELATED CALCIUM DYNAMICS IN LAMPREY MOTONEURONS AS REVEALED BY VIDEO-RATE CONFOCAL MICROSCOPY [J].

BACSKAI, BJ ;

WALLEN, P ;

LEVRAM, V ;

GRILLNER, S ;

TSIEN, RY .

NEURON, 1995, 14 (01) :19-28

[5] NEUROPEPTIDE-Y-IMMUNOREACTIVE SPINAL NEURONS MAKE CLOSE APPOSITIONS ON AXONS OF PRIMARY SENSORY AFFERENTS [J].

BONGIANNI, F ;

CHRISTENSON, J ;

HOKFELT, T ;

GRILLNER, S .

BRAIN RESEARCH, 1990, 523 (02) :337-341

[6] THE ROLE OF PUTATIVE EXCITATORY AMINO-ACID NEUROTRANSMITTERS IN THE INITIATION OF LOCOMOTION IN THE LAMPREY SPINAL-CORD .1. THE EFFECTS OF EXCITATORY AMINO-ACID ANTAGONISTS [J].

BRODIN, L ;

GRILLNER, S .

BRAIN RESEARCH, 1985, 360 (1-2) :139-148

[7] N-METHYL-D-ASPARTATE (NMDA), KAINATE AND QUISQUALATE RECEPTORS AND THE GENERATION OF FICTIVE LOCOMOTION IN THE LAMPREY SPINAL-CORD [J].

BRODIN, L ;

GRILLNER, S ;

ROVAINEN, CM .

BRAIN RESEARCH, 1985, 325 (1-2) :302-306

[8] A SPINAL PROJECTION OF 5-HYDROXYTRYPTAMINE NEURONS IN THE LAMPREY BRAIN-STEM - EVIDENCE FROM COMBINED RETROGRADE TRACING AND IMMUNOHISTOCHEMISTRY [J].

BRODIN, L ;

BUCHANAN, JT ;

HOKFELT, T ;

GRILLNER, S ;

VERHOFSTAD, AAJ .

NEUROSCIENCE LETTERS, 1986, 67 (01) :53-57

[9] NEUROTENSIN-LIKE PEPTIDES IN THE CNS OF LAMPREYS - CHROMATOGRAPHIC CHARACTERIZATION AND IMMUNOHISTOCHEMICAL LOCALIZATION WITH REFERENCE TO AMINERGIC MARKERS [J].

BRODIN, L ;

THEORDORSSON, E ;

CHRISTENSON, J ;

CULLHEIM, S ;

HOKFELT, T ;

BROWN, JC ;

BUCHAN, A ;

PANULA, P ;

VERHOFSTAD, AAJ ;

GOLDSTEIN, M .

EUROPEAN JOURNAL OF NEUROSCIENCE, 1990, 2 (12) :1095-1109

[10] COMPUTER-SIMULATIONS OF N-METHYL-D-ASPARTATE RECEPTOR-INDUCED MEMBRANE-PROPERTIES IN A NEURON MODEL [J].

BRODIN, L ;

TRAVEN, HGC ;

LANSNER, A ;

WALLEN, P ;

EKEBERG, O ;

GRILLNER, S .

JOURNAL OF NEUROPHYSIOLOGY, 1991, 66 (02) :473-484

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