The intrinsic function of a motor system -: from ion channels to networks and behavior

被引:89
作者
Grillner, S [1 ]
Cangiano, L [1 ]
Hu, GY [1 ]
Thompson, R [1 ]
Hill, R [1 ]
Wallén, P [1 ]
机构
[1] Karolinska Inst, Dept Neurosci, Nobel Inst Neurophysiol, SE-17177 Stockholm, Sweden
关键词
locomotion; networks; ion channel; modulation; modeling; behavior;
D O I
10.1016/S0006-8993(00)03088-2
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The forebrain, brainstem and spinal cord contribution to the control of locomotion is reviewed in this article. The lamprey is used as an experimental model since it allows a detailed cellular analysis of the neuronal network underlying locomotion. The focus is on cellular mechanisms that are important for the pattern generation, as well as different types of pre- and postsynaptic modulation. This experimental model is bridging the gap between the molecular and cellular level to the network and behavioral level. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:224 / 236
页数:13
相关论文
共 80 条
[31]   NEUROBIOLOGICAL BASES OF RHYTHMIC MOTOR ACTS IN VERTEBRATES [J].
GRILLNER, S .
SCIENCE, 1985, 228 (4696) :143-148
[32]   DOES THE CENTRAL PATTERN GENERATION FOR LOCOMOTION IN LAMPREY DEPEND ON GLYCINE INHIBITION [J].
GRILLNER, S ;
WALLEN, P .
ACTA PHYSIOLOGICA SCANDINAVICA, 1980, 110 (01) :103-105
[33]   NEURAL NETWORKS THAT COORDINATE LOCOMOTION AND BODY ORIENTATION IN LAMPREY [J].
GRILLNER, S ;
DELIAGINA, T ;
EKEBERG, O ;
ELMANIRA, A ;
HILL, RH ;
LANSNER, A ;
ORLOVSKY, GN ;
WALLEN, P .
TRENDS IN NEUROSCIENCES, 1995, 18 (06) :270-279
[34]  
GRILLNER S, 1974, EXP BRAIN RES, V20, P459
[35]   SIMULATION OF THE SEGMENTAL BURST GENERATING NETWORK FOR LOCOMOTION IN LAMPREY [J].
GRILLNER, S ;
BUCHANAN, JT ;
LANSNER, A .
NEUROSCIENCE LETTERS, 1988, 89 (01) :31-35
[36]  
GRILLNER S, 1997, COMPUT NEUR, P3
[37]  
GRILLNER S, 1981, ACTA PHYSL SCAND, V113
[38]  
Grillner S., 1981, HDB PHYSL 1, VII, P1179, DOI [DOI 10.1126/SCIENCE.1245629, DOI 10.1002/CPHY.CP010226]
[39]   COMPUTER-SIMULATION OF THE SEGMENTAL NEURAL NETWORK GENERATING LOCOMOTION IN LAMPREY BY USING POPULATIONS OF NETWORK INTERNEURONS [J].
HELLGREN, J ;
GRILLNER, S ;
LANSNER, A .
BIOLOGICAL CYBERNETICS, 1992, 68 (01) :1-13
[40]  
HU GY, 2000, IN PRESS ACTA PHYS A, V19