Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging

被引：44

作者：

Bezemer, Rick ^{[1
,2
]}

Legrand, Matthieu ^{[1
,3
]}

Klijn, Eva ^{[2
]}

Heger, Michal ^{[4
]}

Post, Ivo C. J. H. ^{[4
]}

van Gulik, Thomas M. ^{[4
]}

Payen, Didier ^{[3
]}

Ince, Can ^{[1
,2
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Translat Physiol, NL-1105 AZ Amsterdam, Netherlands

[2] Erasmus Univ, Dept Intens Care, Erasmus Med Ctr, Rotterdam, Netherlands

[3] Univ Paris, Dept Anesthesiol & Crit Care, Lariboisiere Hosp, AP HP, F-75252 Paris, France

[4] Univ Amsterdam, Acad Med Ctr, Dept Expt Surg, NL-1105 AZ Amsterdam, Netherlands

来源：

OPTICS EXPRESS | 2010年 / 18卷 / 14期

关键词：

BLOOD-FLOW; REPERFUSION; ISCHEMIA; DOPPLER; HYPOXIA; SKIN;

D O I：

10.1364/OE.18.015054

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Laser speckle imaging (LSI) is able to provide full-field perfusion maps of the renal cortex and allows quantification of the average LSI perfusion within an arbitrarily set region of interest and the recovery of LSI perfusion histograms within this region. The aim of the present study was to evaluate the use of LSI for mapping renal cortical microvascular perfusion and to demonstrate the capability of LSI to assess renal perfusion heterogeneities. The main findings were that: 1) full-field LSI measurements of renal microvascular perfusion were highly correlated to single-point LDV measurements; 2) LSI is able to detect differences in reperfusion dynamics following different durations of ischemia; and 3) renal microvascular perfusion heterogeneities can be quantitatively assessed by recovering LSI perfusion histograms. (C) 2010 Optical Society of America

引用

页码：15054 / 15061

页数：8

共 28 条

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