Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging

被引：44

作者：

Bezemer, Rick ^{[1
,2
]}

Legrand, Matthieu ^{[1
,3
]}

Klijn, Eva ^{[2
]}

Heger, Michal ^{[4
]}

Post, Ivo C. J. H. ^{[4
]}

van Gulik, Thomas M. ^{[4
]}

Payen, Didier ^{[3
]}

Ince, Can ^{[1
,2
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Translat Physiol, NL-1105 AZ Amsterdam, Netherlands

[2] Erasmus Univ, Dept Intens Care, Erasmus Med Ctr, Rotterdam, Netherlands

[3] Univ Paris, Dept Anesthesiol & Crit Care, Lariboisiere Hosp, AP HP, F-75252 Paris, France

[4] Univ Amsterdam, Acad Med Ctr, Dept Expt Surg, NL-1105 AZ Amsterdam, Netherlands

来源：

OPTICS EXPRESS | 2010年 / 18卷 / 14期

关键词：

BLOOD-FLOW; REPERFUSION; ISCHEMIA; DOPPLER; HYPOXIA; SKIN;

D O I：

10.1364/OE.18.015054

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Laser speckle imaging (LSI) is able to provide full-field perfusion maps of the renal cortex and allows quantification of the average LSI perfusion within an arbitrarily set region of interest and the recovery of LSI perfusion histograms within this region. The aim of the present study was to evaluate the use of LSI for mapping renal cortical microvascular perfusion and to demonstrate the capability of LSI to assess renal perfusion heterogeneities. The main findings were that: 1) full-field LSI measurements of renal microvascular perfusion were highly correlated to single-point LDV measurements; 2) LSI is able to detect differences in reperfusion dynamics following different durations of ischemia; and 3) renal microvascular perfusion heterogeneities can be quantitatively assessed by recovering LSI perfusion histograms. (C) 2010 Optical Society of America

引用

页码：15054 / 15061

页数：8

共 28 条

[21] Comparison of instruments for investigation of microcirculatory blood flow and red blood cell concentration
O'Doherty, Jim
McNamara, Paul
Clancy, Neil T.
Enfield, Joey G.
Leahy, Martin J.
[J]. JOURNAL OF BIOMEDICAL OPTICS, 2009, 14 (03)
[22] A non-contact method and instrumentation to monitor renal ischemia and reperfusion with optical spectroscopy
Raman, Rajesh N.
Pivetti, Christopher D.
Matthews, Dennis L.
Troppmann, Christoph
Demos, Stavros G.
[J]. OPTICS EXPRESS, 2009, 17 (02): : 894 - 905
[23] Renal parenchymal oxygenation and hypoxia adaptation in acute kidney injury
Rosenberger, Christian
Rosen, Seymour
Heyman, Samuel N.
[J]. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2006, 33 (10) : 980 - 988
[24] A comparison of two laser-based methods for determination of burn scar perfusion: Laser Doppler versus laser speckle imaging
Stewart, CJ
Frank, R
Forrester, KR
Tulip, J
Lindsay, R
Bray, RC
[J]. BURNS, 2005, 31 (06) : 744 - 752
[25] Walter B, 2002, ACT NEUR S, V81, P197
[26] Theoretical and experimental optimization of laser speckle contrast imaging for high specificity to brain microcirculation
Wang, Zheng
Hughes, Sarah
Dayasundara, Sudath
Menon, Ravi S.
[J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2007, 27 (02) : 258 - 269
[27] Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice
Wu, Liping
Tiwari, Manish M.
Messer, Kurt J.
Holthoff, Joseph H.
Gokden, Neriman
Brock, Robert W.
Mayeux, Philip R.
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2007, 292 (01) : F261 - F268
[28] Intravital videomicroscopy of peritubular capillaries in renal ischemia
Yamamoto, T
Tada, T
Brodsky, SV
Tanaka, H
Noiri, E
Kajiya, F
Goligorsky, MS
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2002, 282 (06) : F1150 - F1155

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