Molecular markers of carcinogenesis

被引：20

作者：

Brandt-Rauf, PW

Pincus, MR

机构：

[1] Columbia Univ, Sch Publ Hlth, Div Environm Hlth Sci, New York, NY 10032 USA

[2] Vet Adm Med Ctr, Dept Pathol & Lab Med, Brooklyn, NY 11209 USA

来源：

PHARMACOLOGY & THERAPEUTICS | 1998年 / 77卷 / 02期

关键词：

growth factors; oncogene proteins; tumor suppressor gene proteins; cancer;

D O I：

10.1016/S0163-7258(97)00111-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The protein products of oncogenes and tumor suppressor genes play critical roles in the development of many cancers. The expression of a number of these proteins can be detected in extracellular fluids such as blood. This article reviews the literature on the application of methods for the detection of the proteins of oncogenes and tumor suppressor genes in the blood of humans with cancer or at risk for the development of cancer. The detection of these proteins in blood may be useful molecular markers of carcinogenesis that could play an important part in cancer diagnosis, prognosis, and prevention. (C) 1998 Elsevier Science, Inc.

引用

收藏

页码：135 / 148

页数：14

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