Synthesis and conformational and biological aspects of carbasugars

被引：307

作者：

Arjona, Odon

Gomez, Ana M.

Cristobal Lopez, J.

Plumet, Joaquin

机构：

[1] CSIC, Inst Quim Organ Gen, E-28006 Madrid, Spain

[2] Univ Complutense, Dept Quim Organ, Fac Quim, E-28040 Madrid, Spain

来源：

CHEMICAL REVIEWS | 2007年 / 107卷 / 05期

关键词：

D O I：

10.1021/cr0203701

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review covers the progress made in the chemistry, synthesis and biology of carbasugars until May 2004. It includes the extensively studied carbapyranoses as well as the scarcely considered carbafuranoses. Specific topics discussed include the natural occurrence of carbasugars, biosynthesis and biological activity of carbasugars, conformational analysis of carbasugars, and the compilation of synthetic methods of carbafuranoses and carbapyranoses.

引用

收藏

页码：1919 / 2036

页数：118

相关论文

共 730 条

[81]

2-G

[82] PROTON AND C-13 NMR-SPECTRA OF 6 PSEUDO-2-ACETAMIDO-2-DEOXY-DL-HEXOPYRANOSES [J].

BOCK, K ;

OGAWA, S ;

ORIHARA, M .

CARBOHYDRATE RESEARCH, 1989, 191 (02) :357-363

[83] A H-1-NMR AND C-13-NMR SPECTROSCOPIC ANALYSIS OF 6 PSEUDOHEXOSES [J].

BOCK, K ;

GUZMAN, JFB ;

OGAWA, S .

CARBOHYDRATE RESEARCH, 1988, 174 :354-359

[84]

Bock K, 1982, ANNU REP NMR SPECTRO, V13, P1

[85] SYNTHESIS OF ANALOGS OF NEPLANOCIN-A - UTILIZATION OF OPTICALLY-ACTIVE DIHYDROXYCYCLOPENTENONES DERIVED FROM CARBOHYDRATES [J].

BORCHERDING, DR ;

SCHOLTZ, SA ;

BORCHARDT, RT .

JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (24) :5457-5461

[86]

BORTHWICK AD, 1995, TETRAHEDRON LETT, V36, P6929, DOI 10.1016/00404-0399(50)1372O-

[87] AN EFFICIENT SYNTHESIS OF A CHIRAL CARBOCYCLIC 2'-DEOXYRIBONUCLEOSIDE SYNTHON BY DIRECTED REDUCTION [J].

BORTHWICK, AD ;

CRAME, AJ ;

EXALL, AM ;

WEINGARTEN, GG .

TETRAHEDRON LETTERS, 1994, 35 (41) :7677-7680

[88] Enolic ortho esters .6. A new 'Pyranose->cyclohexane' transformation via 1,6-dideoxy-1,1-ethylenedioxy-2,3,4-tri-O-methyl-D-xylo-hex-5-enopyranose [J].

Bourke, DG ;

Collins, DJ ;

Hibberd, AI ;

McLeod, MD .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1996, 49 (03) :425-434

[89] Biosynthetic studies on the α-glucosidase inhibitor acarbose:: the chemical synthesis of dTDP-4-amino-4,6-dideoxy-α-D-glucose [J].

Bowers, SG ;

Mahmud, T ;

Floss, HG .

CARBOHYDRATE RESEARCH, 2002, 337 (04) :297-304

[90] CARBOHYDRATE LIGANDS OF THE LEC CELL-ADHESION MOLECULES [J].

BRANDLEY, BK ;

SWIEDLER, SJ ;

ROBBINS, PW .

CELL, 1990, 63 (05) :861-863

← 4 5 6 7 8 9 10 11 12 13 →