The mechanisms underlying endosomal trafficking have been mostly dissected in yeast and mammalian tissue culture cells. Here, we review recent advances in the understanding of the role of endosomal trafficking in Drosophila epithelial cells. We focus on endosomal pathways that control cell polarization, cell growth, cell fate and epithelial cell rearrangement. We expect that mechanistic studies in mammalian cells and functional studies in invertebrates will continue to synergize to provide a comprehensive view of the role of endosomal trafficking in epithelial tissue organization and functions.
机构:
Univ Michigan, Dept Internal Med & Biol Chem, Sch Med, Ann Arbor, MI 48109 USAUniv Michigan, Dept Internal Med & Biol Chem, Sch Med, Ann Arbor, MI 48109 USA
Margolis, B
;
Borg, JP
论文数: 0引用数: 0
h-index: 0
机构:Univ Michigan, Dept Internal Med & Biol Chem, Sch Med, Ann Arbor, MI 48109 USA
机构:
Univ Michigan, Dept Internal Med & Biol Chem, Sch Med, Ann Arbor, MI 48109 USAUniv Michigan, Dept Internal Med & Biol Chem, Sch Med, Ann Arbor, MI 48109 USA
Margolis, B
;
Borg, JP
论文数: 0引用数: 0
h-index: 0
机构:Univ Michigan, Dept Internal Med & Biol Chem, Sch Med, Ann Arbor, MI 48109 USA