Neuronal degeneration and mitochondrial dysfunction

被引:294
作者
Schon, EA
Manfredi, G
机构
[1] Columbia Univ, Dept Neurol, New York, NY 10032 USA
[2] Columbia Univ, Dept Genet & Dev, New York, NY 10032 USA
[3] Cornell Univ, Weill Med Coll, Dept Neurol & Neurosci, New York, NY USA
关键词
D O I
10.1172/JCI200317741
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
[No abstract available]
引用
收藏
页码:303 / 312
页数:10
相关论文
共 66 条
[21]   Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partners Hippi [J].
Gervais, FG ;
Singaraja, R ;
Xanthoudakis, S ;
Gutekunst, CA ;
Leavitt, BR ;
Metzler, M ;
Hackam, AS ;
Tam, J ;
Vaillancourt, JP ;
Houtzager, V ;
Rasper, DM ;
Roy, S ;
Hayden, MR ;
Nicholson, DW .
NATURE CELL BIOLOGY, 2002, 4 (02) :95-105
[22]   Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60 [J].
Hansen, JJ ;
Dürr, A ;
Cournu-Rebeix, I ;
Georgopoulos, C ;
Ang, D ;
Nielsen, MN ;
Davoine, CS ;
Brice, A ;
Fontaine, B ;
Gregersen, N ;
Bross, P .
AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 70 (05) :1328-1332
[23]   Apoptosis is suspended in muscle of mitochondrial encephalomyopathies [J].
Ikezoe, K ;
Nakagawa, M ;
Yan, CZ ;
Kira, J ;
Goto, Y ;
Nonaka, I .
ACTA NEUROPATHOLOGICA, 2002, 103 (06) :531-540
[24]   EVIDENCE FOR IMPAIRMENT OF ENERGY-METABOLISM IN-VIVO IN HUNTINGTONS-DISEASE USING LOCALIZED H-1-NMR SPECTROSCOPY [J].
JENKINS, BG ;
KOROSHETZ, WJ ;
BEAL, MF ;
ROSEN, BR .
NEUROLOGY, 1993, 43 (12) :2689-2695
[25]   A novel X-linked gene, DDP, shows mutations in families with deafness (DFN-1), dystonia, mental deficiency and blindness [J].
Jin, H ;
May, M ;
Tranebjaerg, L ;
Kendall, E ;
Fontan, G ;
Jackson, J ;
Subramony, SH ;
Arena, F ;
Lubs, H ;
Smith, S ;
Stevenson, R ;
Schwartz, C ;
Vetrie, D .
NATURE GENETICS, 1996, 14 (02) :177-180
[26]   Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis [J].
Klivenyi, P ;
Ferrante, RJ ;
Matthews, RT ;
Bogdanov, MB ;
Klein, AM ;
Andreassen, OA ;
Mueller, G ;
Wermer, M ;
Kaddurah-Daouk, R ;
Beal, MF .
NATURE MEDICINE, 1999, 5 (03) :347-350
[27]  
Kong JM, 1998, J NEUROSCI, V18, P3241
[28]   Energy metabolism defects in Huntington's disease and effects of coenzyme Q(10) [J].
Koroshetz, WJ ;
Jenkins, BG ;
Rosen, BR ;
Beal, MF .
ANNALS OF NEUROLOGY, 1997, 41 (02) :160-165
[29]   ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases [J].
Koseki, T ;
Inohara, N ;
Chen, S ;
Nunez, G .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (09) :5156-5160
[30]   Mitochondrial control of cell death [J].
Kroemer, G ;
Reed, JC .
NATURE MEDICINE, 2000, 6 (05) :513-519