Synthesis of pyrimido[4,5-b]quinolines in the reaction of 6-aminopyrimidines with dimedone and benzaldehydes

被引：57

作者：

Quiroga, J ^{[1
]}

Hormaza, A

Insuasty, B

Ortiz, AJ

Sanchez, A

Nogueras, M

机构：

[1] Univ Valle, Dept Chem, Cali AA25360, Colombia

[2] Univ Jaen, Dept Inorgan & Organ Chem, Jaen 23071, Spain

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1998年 / 35卷 / 01期

关键词：

D O I：

10.1002/jhet.5570350142

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 6-aminopyrimidines 1a,b with dimedone (2) and p-substituted benzaldehydes 3a-d in ethanol afforded in all cases new regiospecific synthesis of tricyclic, linear 5-aryl-5,6,7,8,9,10-hexahydropyrimido[4,5-b]quinolines 4a-h in good yields, The linear structures and hence the regiospecificity of the reaction were established by nmr measurements.

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页码：231 / 233

页数：3

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