Mothers' preferences and willingness to pay for vaccinating daughters against human papillomavirus

被引:66
作者
Brown, Derek S. [1 ]
Johnson, F. Reed [1 ]
Poulos, Christine [1 ]
Messonnier, Mark L. [2 ]
机构
[1] RTI Int, Res Triangle Pk, NC 27709 USA
[2] Ctr Dis Control & Prevent, Immunizat Serv Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30329 USA
关键词
Conjoint analysis; Human papillomavirus vaccine; Cost-benefit analysis; Preferences; Demand; Mothers; Adolescent girls; Discrete choice experiment; HPV VACCINE; PRIVATE DEMAND; HEALTH; INFECTION; ATTITUDES; COST; RECOMMENDATIONS; ACCEPTABILITY; IMMUNIZATION; PREVALENCE;
D O I
10.1016/j.vaccine.2009.12.024
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A choice-format, conjoint-analysis survey was developed and fielded to estimate how features of human papillomavirus (HPV) vaccines affect mothers' perceived benefit and stated vaccine uptake for daughters. Data were collected from a national sample of 307 U.S. mothers of girls aged 13-17 years who had not yet received an HPV vaccine. Preferences for four features of HPV vaccines were evaluated: protection against cervical cancer, protection against genital warts, duration of protection, and cost. We estimate that mean maximum willingness-to-pay (WTP)-an economic measure of the total benefits to consumers-for current HPV vaccine technology ranges between $560 and $660. All vaccine features were statistically significant determinants of WTP and uptake. Mothers were willing to pay $238 more for a vaccine that provides 90% protection for genital warts relative to a vaccine that provides no protection against warts. WTP for lifetime protection vs. 10 years protection was $245. Mothers strongly valued greater cervical cancer efficacy, with 100% protection against cervical cancers the most desired feature overall. Adding a second HPV vaccine choice to U.S. consumers' alternatives is predicted to increase stated uptake by 16%. Several features were significantly associated with stated choices and uptake: age of mother, Face/ethnicity, household income, and concern about HPV risks. These findings provide new data on how HPV vaccines are viewed and valued by mothers, and how uptake may change in the context of evolving vaccine technology and as new data ate reported on duration and efficacy. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1702 / 1708
页数:7
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[21]   Best-worst scaling: What it can do for health care research and how to do it [J].
Flynn, Terry N. ;
Louviere, Jordan J. ;
Peters, Tim J. ;
Coast, Joanna .
JOURNAL OF HEALTH ECONOMICS, 2007, 26 (01) :171-189
[22]   Human Papillomavirus (HPV) Vaccines: Limited Cross-Protection against Additional HPV Types [J].
Herrero, Rolando .
JOURNAL OF INFECTIOUS DISEASES, 2009, 199 (07) :919-922
[23]   Cost-benefit analysis of routine childhood vaccination against chickenpox in Taiwan: decision from different perspectives [J].
Hsu, HC ;
Lin, RS ;
Tung, TH ;
Chen, THH .
VACCINE, 2003, 21 (25-26) :3982-3987
[24]   Assessing the annual economic burden of preventing and treating anogenital human papillomavirus-related disease in the US - Analytic framework and review of the literature [J].
Insinga, RP ;
Dasbach, EJ ;
Elbasha, EH .
PHARMACOECONOMICS, 2005, 23 (11) :1107-1122
[25]  
Jensen Megan E, 2009, WMJ, V108, P203
[26]  
JIT M, 2008, BMJ-BRIT MED J, V377, pA769
[27]  
Johnson FR, 2000, HEALTH ECON, V9, P295, DOI 10.1002/1099-1050(200006)9:4<295::AID-HEC520>3.3.CO
[28]  
2-4
[29]   Rates of human papillomavirus vaccination, attitudes about vaccination, and human papillomavirus prevalence in young women [J].
Kahn, Jessica A. ;
Rosenthal, Susan L. ;
Jin, Yan ;
Huang, Bin ;
Namakydoust, Azadeh ;
Zimet, Gregory D. .
OBSTETRICS AND GYNECOLOGY, 2008, 111 (05) :1103-1110
[30]   Human Papillomavirus Vaccine Recommendations and Agreement with Mandated Human Papillomavirus Vaccination for 11-to-12-Year-Old Girls: a Statewide Survey of Texas Physicians [J].
Kahn, Jessica A. ;
Cooper, H. Paul ;
Vadaparampil, Susan T. ;
Pence, Barbara C. ;
Weinberg, Armin D. ;
LoCoco, Salvatore J. ;
Rosenthal, Susan L. .
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2009, 18 (08) :2325-2332