Ethanolamine utilization in bacterial pathogens: roles and regulation

被引：249

作者：

Garsin, Danielle A. ^{[1
]}

机构：

[1] Univ Texas Hlth Sci Ctr Houston, Dept Microbiol & Mol Genet, Houston, TX 77030 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2010年 / 8卷 / 04期

关键词：

RESPONSIVE TRANSCRIPTION ANTITERMINATION; SALMONELLA-ENTERICA ENCODES; AMMONIA-LYASE; PSEUDOMONAS-AERUGINOSA; ESCHERICHIA-COLI; CLOSTRIDIAL FERMENTATIONS; ENTEROCOCCUS-FAECALIS; MICROBIAL-METABOLISM; CRYSTAL-STRUCTURE; AMINO-ALCOHOLS;

D O I：

10.1038/nrmicro2334

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Ethanolamine is a compound that can be readily derived from cell membranes and that some bacteria can use as a source of carbon and/or nitrogen. The complex biology and chemistry of this process has been under investigation since the 1970s, primarily in one or two species. However, recent investigations into ethanolamine utilization have revealed important and intriguing differences in gene content and regulatory mechanisms among the bacteria that harbour this catabolic ability. In addition, many reports have connected this process to bacterial pathogenesis. In this Progress article, I discuss the latest research on the phylogeny and regulation of ethanolamine utilization and its possible roles in bacterial pathogenesis.

引用

页码：290 / 295

页数：6

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