Optoacoustic imaging using interferometric measurement of surface displacement

被引：49

作者：

Carp, SA

Guerra, A

Duque, SQ

Venugopalan, V ^{[1
]}

机构：

[1] Univ Calif Irvine, Beckman Laser Inst, Laser Microbeam & Med Program, Irvine, CA 92697 USA

[2] Univ Calif Irvine, Dept Chem Engn & Mat Sci, Irvine, CA 92697 USA

来源：

APPLIED PHYSICS LETTERS | 2004年 / 85卷 / 23期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1063/1.1831569

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We describe an optoacoustic imaging technique based on time-resolved measurements of laser-induced thermoelastic expansion. Tomographic images of tissue phantoms are formed using such measurements made at several locations following irradiation with a Q-switched Nd:YAG (lambda=1064 nm) laser pulse. Our system is based on a modified Mach-Zehnder interferometer that measures surface displacement with a temporal resolution of 4 ns and a displacement sensitivity of 0.3 nm. Images formed from data sets acquired from several highly scattering tissue phantoms provide better than 200 mum resolution and show great promise for high-resolution noninvasive imaging of heterogeneous tissues at depths approaching 1 cm. (C) 2004 American Institute of Physics.

引用

页码：5772 / 5774

页数：3

共 19 条

[1]

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