The ProDom database of protein domain families: more emphasis on 3D

被引:226
作者
Bru, C [1 ]
Courcelle, E [1 ]
Carrre, S [1 ]
Beausse, Y [1 ]
Dalmar, S [1 ]
Kahn, D [1 ]
机构
[1] CNRS, INRA, Lab Interact Plantes Microorgan, F-31326 Castanet Tolosan, France
关键词
D O I
10.1093/nar/gki034
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ProDom is a comprehensive database of protein domain families generated from the global comparison of all available protein sequences. Recent improvements include the use of three-dimensional (313) information from the SCOP database; a completely redesigned web interface (http://www. toulouse.inra.fr/prodom.htmi); visualization of ProDom domains on 3D structures; coupling of ProDom analysis with the Geno3D homology modelling server; Bayesian inference of evolutionary scenarios for ProDom families. In addition, we have developed ProDom-SG, a ProDom-based server dedicated to the selection of candidate proteins for structural genomics.
引用
收藏
页码:D212 / D215
页数:4
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