A comparison of anesthetic quality in propofol-spinal anesthesia and propofol-fentanyl anesthesia for total knee arthroplasty in elderly patients

Study Objective: To compare propofol plus spinal anesthesia during spontaneous ventilation using the Laryngeal Mask Airway and propofol plus fentanyl anesthesia during mechanical ventilation with an endotracheal tube on qualify of recovery after anesthesia. Design: Prospective, randomized, study. Setting: Hirosaki National Hospital. Patients: 150 patients (aged > 70 years) undergoing total knee arthroplasty. Interventions: Patients were divided randomly into two groups, to receive spontaneous ventilation with a Laryngeal Mask Airway during propofol-spinal anesthesia, or to receive Propofol-fentanyl anesthesia with mechanical ventilation via endotracheal tube. Measurements: Quality of anesthesia recovery such as nausea. vomiting headache. Pain throat, hoarse voice, back pain, dizziness, feeling, comfortable, dreaming recovery times in recovery of anesthesia, recovery times. postoperative pain, confusion, was assessed. Main Results: The frequency of postoperative pain throat, hoarse voice. and nausea was signficantly lower in the propofol-spinal anesthesia group than the propol-fentanyl anesthesia group. The time to extubation, emergence, response to commands. and orientation were significantly faster (p < 0.001) in the propofol-spinal anesthesia group than the propofol-fentanyl anesthesia group. The frequency of postoperative confusion occurring in the propofol-spinal anesthesia group during the first 24 hours was significantly lower than. that of the propofol-fentanyl anesthesia group (p = 0.03). Conclusions: Propofol-spinal anesthesia provided better and faster recovery than did propofol-fentanyl anesthesia for elderly patients undergoing total knee arthroplasty. (C) 2004, by Elsevier Inc.