Peptide self-assembly as a model of proteins in the pre-genomic world

被引：32

作者：

Ghosh, I

Chrnielewski, J

机构：

[1] Univ Arizona, Dept Chem, Tucson, AZ 85721 USA

[2] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2004年 / 8卷 / 06期

基金：

美国国家航空航天局; 美国国家科学基金会;

关键词：

D O I：

10.1016/j.cbpa.2004.09.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Excellent catalytic efficiency has been obtained within a series of self replicating peptides, and nucleobase inclusion into a salt-switchable self replicating peptide is found to override the switch. Interestingly, cross-catalytic formation of an RNA aptamer is reported with a cationic peptide, and novel, amide-based biopolymers have been designed to self assemble.

引用

收藏

页码：640 / 644

页数：5

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