A general method for the vinylation of nitrones.: Synthesis of allyl hydroxylamines and allyl amines

被引：23

作者：

Merino, P ^{[1
]}

Anoro, S ^{[1
]}

Franco, S ^{[1
]}

Gascon, JM ^{[1
]}

Martin, V ^{[1
]}

Merchan, FL ^{[1
]}

Revuelta, J ^{[1
]}

Tejero, T ^{[1
]}

Tuñon, V ^{[1
]}

机构：

[1] Univ Zaragoza, Fac Ciencias, Dept Quim Organ, ICMA, E-50009 Aragon, Spain

来源：

SYNTHETIC COMMUNICATIONS | 2000年 / 30卷 / 16期

关键词：

D O I：

10.1080/00397910008087449

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An examination of the vinylation of several nitrones is presented. Whereas a complete diastereofacial discrimination was observed upon the addition of vinyl organometallic reagents to alpha-alkoxy nitrones, the same reaction with alpha-amino nitrones pave syn adducts in all cases, with the only exception of a L-serine-derived alpha-amino monoprotected nitrone. The obtained allyl hydroxylamines were easily transformed into synthetically valuable allyl amines.

引用

页码：2989 / 3021

页数：33

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