机构:Univ London Kings Coll Hosp, Children Nationwide Reg Neonatal Intens Care Ctr, Ruskin Wing, London SE5 9RS, England
Greenough, A
Kavvadia, V
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机构:Univ London Kings Coll Hosp, Children Nationwide Reg Neonatal Intens Care Ctr, Ruskin Wing, London SE5 9RS, England
Kavvadia, V
Laubscher, B
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机构:Univ London Kings Coll Hosp, Children Nationwide Reg Neonatal Intens Care Ctr, Ruskin Wing, London SE5 9RS, England
Laubscher, B
Milner, AD
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机构:Univ London Kings Coll Hosp, Children Nationwide Reg Neonatal Intens Care Ctr, Ruskin Wing, London SE5 9RS, England
Milner, AD
机构:
[1] Univ London Kings Coll Hosp, Children Nationwide Reg Neonatal Intens Care Ctr, Ruskin Wing, London SE5 9RS, England
[2] United Med & Dent Sch Guys & St Thomas Hosp, St Thomas Hosp, Dept Paediat, London SE1 7EH, England
来源:
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
|
1998年
/
78卷
/
02期
关键词:
high frequency oscillation;
prematurity;
delivered volume;
D O I:
10.1136/fn.78.2.F148
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
Aim-To examine the delivered volume during "high volume strategy" high frequency oscillation, used as rescue treatment in preterm infants; and to identify factors, other than frequency and oscillatory amplitude, influencing the magnitude of volume delivery. Method-Twenty infants (median gestational age 29 weeks) were studied on 45 occasions. Two oscillator types were used (SensorMedics and SLE). Delivered volume was measured under clinical conditions with the arterial blood gases within a predetermined range. A specially calibrated pneumotachograph system was used. Results-Overall, the median delivered volume was 2.4 ml/kg (range 1.0 to 3.6 ml/kg); on 32 occasions the delivered volume was greater than 2.0 ml/kg and on seven greater than 3.0 ml/kg. The delivered volume related significantly to disease severity; there was an inverse correlation between delivered volume and both the oxygenation index (OI) (r=-0.51) and AaDO(2) (r=-0.54). Conclusion-Delivered volume during HFO may, in certain infants, exceed the anatomical dead space, permitting some direct alveolar ventilation.