Palladium-Catalyzed Direct Arylations, Alkenylations, and Benzylations through C-H Bond Cleavages with Sulfamates or Phosphates as Electrophiles

被引：183

作者：

Ackermann, Lutz ^{[1
]}

Barfuesser, Sebastian ^{[1
]}

Pospech, Jola ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 04期

关键词：

INTERMOLECULAR DIRECT ARYLATION; ARYL CHLORIDES; PHOSPHINE OXIDES; SUZUKI-MIYAURA; HETEROCYCLES; ACTIVATION; FUNCTIONALIZATION; PRELIGANDS; HETEROARENES; ALKYLATION;

D O I：

10.1021/ol9028034

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalytic system comprised of Pd(OAc)(2) and bidentate ligand dppe enabled first direct arylations with moisture-stable aryl sulfamates as electrophiles, and proved applicable to unprecedented C-H bond functionalizations with easily accessible alkenyl phosphates as well as benzyl phosphates.

引用

页码：724 / 726

页数：3

共 54 条

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Ackermann, L
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[5] Assisted ruthenium-catalyzed C-H bond activation: Carboxylic acids as cocatalysts for generally applicable direct arylations in apolar solvents
Ackermann, Lutz
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Ackermann, Lutz
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[8] Domino N-H/C-H bond activation: Palladium-catalyzed synthesis of annulated heterocycles using dichloro(hetero)arenes
Ackermann, Lutz
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[9] Catalytic arylations with challenging substrates: From air-stable HASPO preligands to indole syntheses and C-H-bond functionalizations
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[J]. SYNLETT, 2007, (04) : 507 - 526
[10] Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by C-H Bond Cleavage
Ackermann, Lutz
Vicente, Ruben
Kapdi, Anant R.
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (52) : 9792 - 9826

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