TiO2 nanotube structures for enhanced cell and biological functionality

被引：19

作者：

Brammer, Karla S. ^{[1
]}

Oh, Seunghan ^{[1
,2
]}

Frandsen, Christine J. ^{[1
]}

Jin, Sungho ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Mat Sci & Engn, La Jolla, CA 92093 USA

[2] Wonkwang Univ, Dept Dent Biomat, Coll Dent, Iksan, South Korea

来源：

JOM | 2010年 / 62卷 / 04期

关键词：

TITANIUM; SURFACES; GROWTH; BONE;

D O I：

10.1007/s11837-010-0059-x

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Nanostructures have pronounced effects on biological processes such as growth of cells and their functionality. Advances in biomaterial surface structure and design have resulted in improved tissue engineering. Nanotechnology can be utilized for optimization of titanium implants with a formation of vertically aligned TiO2 nanotube arrays on the implant surface. The anodic oxidation of the titanium implant surface to form a TiO2 nanotube array involves electrochemical processes and self assembly. In this paper, the mechanism of nanotube formation, nanotube bio-characteristics, and their emerging role in soft and hard tissue engineering as well as in regenerative medicine will be reviewed, and the beneficial effects of surface nanotubes on cell adhesion, proliferation, and functionality will be discussed in relation to potential orthopedics applications.

引用

页码：50 / 55

页数：6

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