[1] Dipartimento Chim Sostanze Nat, I-80131 Naples, Italy
来源:
JOURNAL OF NATURAL PRODUCTS
|
1998年
/
61卷
/
01期
关键词:
D O I:
10.1021/np970323h
中图分类号:
Q94 [植物学];
学科分类号:
071001 ;
摘要:
Further investigation of the Caribbean marine sponge Agelas dispar for biologically active constituents has led to the isolation of the novel bromopyrrole alkaloids longamide B (1), and clathramides C (2) and D (3), whose structures have been determined by spectroscopic methods. Isolation of the known keramadine (4) and of the ecdysonic sterols ecdysterone (5) and ajugasterone C (6) is also reported. The antimicrobial activities of the isolated bromopyrrole alkaloids is summarized.