1-Aryl-4,6-diamino-1,2-dihydrotriazine as antimalarial agent: a new synthetic route

被引：36

作者：

Kidwai, M ^{[1
]}

Mothsra, P

Mohan, R

Biswas, S

机构：

[1] Univ Delhi, Dept Chem, Delhi 110007, India

[2] Malaria Res Ctr, Delhi 110054, India

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2005年 / 15卷 / 04期

关键词：

D O I：

10.1016/j.bmcl.2004.12.049

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Some novel derivatives of 1-aryl-4,6-diamino-1,2-dihydrotriazines have been synthesized using neat technology under microwaves. These were tested in vitro against both sensitive and resistant Plasmodium falciparum strains for antimalarial activity. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：915 / 917

页数：3

共 21 条

[1] IRREVERSIBLE ENZYME INHIBITORS .101. A MODIFIED SYNTHESIS OF 2-SUBSTITUTED-4,6-DIAMINO-1,2-DIHYDRO-2-METHYL-1-PHENYL-S-TRIAZINES(1,2) [J].