IRREVERSIBLE ENZYME INHIBITORS .101. A MODIFIED SYNTHESIS OF 2-SUBSTITUTED-4,6-DIAMINO-1,2-DIHYDRO-2-METHYL-1-PHENYL-S-TRIAZINES(1,2)

被引：4

作者：

BAKER, BR

JOHNSON, MA

机构：

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1967年 / 4卷 / 03期

关键词：

D O I：

10.1002/jhet.5570040334

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：447 / &

共 23 条

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[2] FACTORS IN DESIGN OF ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS [J].

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[3] IRREVERSIBLE ENZYME INHIBITORS .83. CANDIDATE ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE .8. DERIVATIVES 2.4-DIAMINOPYRIMIDINE .2. [J].

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[4] ANALOGS OF TETRAHYDROFOLIC ACID .27. HYDROPHOBIC BONDING TO DIHYDROFOLIC REDUCTASE BY 2-AMINO-4,6-DISUBSTITUTED-5-ALKYLPYRIMIDINES AND 1-ALKYL-4,6-DIAMINO-1,2-DIHYDRO-S-TRIAZINES [J].

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[5] IRREVERSIBLE ENZYME INHIBITORS .71. CANDIDATE ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE .5. DERIVATIVES OF 6-PHENYLPYRIMIDINE [J].

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SHAPIRO, HS .

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[6] ANALOGS OF TETRAHYDROFOLIC ACID .23. 1-(OMEGA-PHENYLALKYL)-4,6-DIAMINO-1,2-DIHYDRO-S-TRIAZINES AS INHIBITORS OF DIHYDROFOLIC REDUCTASE [J].

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[7]

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[8] IRREVERSIBLE ENZYME INHIBITORS .68. 2-AMINO-5-(P-BROMOACETAMIDOPHENOXYPROPYL)-6-PHENYL-4-PYRIMIDINOL AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR OF DIHYDROFOLIC REDUCTASE [J].

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[9]

BAKER BR, 1966, J PHARM SCI, V55, P1417, DOI 10.1002/jps.2600551218

[10] IRREVERSIBLE ENZYME INHIBITORS 100 - INHIBITORS OF THYMIDINE PHOSPHORYLASE .8. 6-(P-BROMOACETAMIDOBENZYL)URACIL AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR [J].

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