IRREVERSIBLE ENZYME INHIBITORS 100 - INHIBITORS OF THYMIDINE PHOSPHORYLASE .8. 6-(P-BROMOACETAMIDOBENZYL)URACIL AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR

被引：8

作者：

BAKER, BR

KAWAZU, M

机构：

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1967年 / 56卷 / 09期

关键词：

D O I：

10.1002/jps.2600560907

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

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页码：1086 / &

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共 15 条

[1] NON-CLASSICAL ANTIMETABOLITES .6. 4-(IODOACETAMIDO)-SALICYLIC ACID, AN EXO-ALKYLATING IRREVERSIBLE INHIBITOR [J].

BAKER, BR ;

LEE, WW ;

TONG, E .

JOURNAL OF THEORETICAL BIOLOGY, 1962, 3 (03) :459-&

[2] IRREVERSIBLE ENZYME INHIBITORS .75. INHIBITORS OF THYMIDINE PHOSPHORTLASE .I. MODE OF RIBOFURANOSE BINDING [J].

BAKER, BR .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :297-&

[3] FACTORS IN DESIGN OF ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS [J].

BAKER, BR .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1964, 53 (04) :347-&

[4] IRREVERSIBLE ENZYME INHIBITORS .77. INHIBITORS OF THYMIDINE PHOSPHORYLASE .3. HYDROPHOBIC BONDING BY 1-SUBSTITUTED URACILS CONTAINING ADDITIONAL SUBSTITUENTS AT 5 AND 6 POSITIONS [J].

BAKER, BR ;

KAWAZU, M ;

SANTI, DV ;

SCHWAN, TJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :304-&

[5] IRREVERSIBLE ENZYME INHIBITORS .80. INHIBITORS OF THYMIDINE PHOSPHORYLASE .6. HYDROPHOBIC BONDING WITH 6 SUBSTITUENTS ON ACIDIC 5-NITRO- AND 5-BROMOURACILS [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :316-&

[6] IRREVERSIBLE ENZYME INHIBITORS .79. INHIBITORS OF THYMIDINE PHOSPHORYLASE .V. MODE OF PYRIMIDINE BINDING [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :313-&

[7] IRREVERSIBLE ENZYME INHIBITORS 99 - INHIBITORS OF THYMIDINE PHOSPHORYLASE .7. FURTHER STUDIES ON HYDROPHOBIC BONDING WITH HYDROCARBON SUBSTITUENTS ON ACIDIC URACILS [J].

BAKER, BR ;

KAWAZU, M ;

MCCLURE, JD .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1967, 56 (09) :1081-&

[8] IRREVERSIBLE ENZYME INHIBITORS .76. INHIBITORS OF THYMIDINE PHOSPHORYLASE .2. HYDROPHOBIC BONDING BY 1-SUBSTITUTED URACILS [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :302-&

[9] IRREVERSIBLE ENZYME INHIBITORS .78. INHIBITORS OF THYMIDINE PHOSPHORYLASE .4. HYDROPHOBIC BONDING BY URACILS SUBSTITUTED AT 5 AND 6 POSITIONS [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :311-&

[10] ANALOGS OF TETRAHYDROFOLIC ACID .39(1,2). SELECTIVE BROMOACYLATION OF POLYFUNCTIONAL MOLECULES FOR SYNTHESIS OF ACTIVE-SITE-DIRECTED IRREVERSIBLE ENZYME INHIBITORS [J].

BAKER, BR ;

SANTI, DV ;

COWARD, JK ;

SHAPIRO, HS ;

JORDAAN, JH .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1966, 3 (04) :425-&