Synthesis of functionalized Co0.5Zn0.5Fe2O4 nanoparticles for biomedical applications

被引:19
作者
Bohara, R. A. [1 ]
Yadav, H. M. [1 ]
Thorat, N. D. [2 ]
Mali, S. S. [3 ]
Hong, C. K. [3 ]
Nanaware, S. G. [1 ]
Pawar, S. H. [1 ]
机构
[1] DY Patil Univ, Ctr Interdisciplinary Res, Kolhapur 416006, Maharashtra, India
[2] Sungkyunkwan Univ, Sch Med, Samsung Biomed Res Inst, Dept Mol Cell Biol, Suwon 440746, South Korea
[3] Chonnam Natl Univ, Adv Chem Engn Dept, Kwangju 500757, South Korea
关键词
Magnetic nanoparticles; Amine functionalization; Superparamagnetic; Biocompatibility; MAGNETITE NANOPARTICLES; THERMAL-DECOMPOSITION; CO; TEMPERATURE; UNIFORM; MN;
D O I
10.1016/j.jmmm.2014.11.063
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
In this paper, we report a simple one step method for the synthesis of uniform, water dispersible amine functionalized Co0.5Zn0.5Fe2O4 nanoparticles (AF-CZF) of size about 6 nm. The synthesis process was accomplished by refluxing Fe(acac)(3), Co(acac)(2) and Zn(acac)(2) in diethylene glycol and ethanolamine. The magnetic nanoparticles were characterized by XRD, TGDTA, FTIR, SEM and TEM techniques. Their magnetic properties were also studied by using SQUID. The synthesized particles show super paramagnetism at room temperature. AF-CZF nanoparticles exhibit good cell viability, which is above 95% at a concentration of 80 mu g mL(-1) on MCF7 cell line. The AF-CZF can be a new versatile platform for many interesting biomedical applications. (C) 2014 Elsevier B.V. All rights reserved
引用
收藏
页码:397 / 401
页数:5
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