A bacterial RNA that functions as both a tRNA and an mRNA

被引：116

作者：

Muto, A ^{[1
]}

Ushida, C ^{[1
]}

Himeno, H ^{[1
]}

机构：

[1] Hirosaki Univ, Fac Sci, Dept Biol, Hirosaki, Aomori 036, Japan

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1998年 / 23卷 / 01期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/S0968-0004(97)01159-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bacterial tmRNA (transfer-messenger RNA, also known as 10Sa RNA) contains a tRNA-like structure in the 5'- and 3'-end sequences and an internal reading frame encoding a 'tag' peptide. The dual function of this molecule as both a tRNA and an mRNA facilitates a trans-translation reaction, in which a ribosome can switch between translation of a truncated mRNA and the tmRNA's tag sequence. The result is a chimeric protein with the tag peptide attached to the C terminus of the truncated peptide.

引用

页码：25 / 29

页数：5

共 36 条

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