Electron microscopy of functional ribosome complexes

被引：46

作者：

Frank, J ^{[1
]}

机构：

[1] Wadsworth Ctr, Howard Hughes Med Inst, Hlth Res Inc, Albany, NY 12201 USA

[2] SUNY Albany, Dept Biomed Sci, Albany, NY 12201 USA

来源：

BIOPOLYMERS | 2003年 / 68卷 / 02期

关键词：

translation; tRNA; EF-G; three-dimensional reconstruction; molecular machines;

D O I：

10.1002/bip.10210

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cryoelectron microscopy has made a number of significant contributions to our understanding of the translation process. The method of single-particle reconstruction is particularly well suited for the study of the dynamics of ribosome-ligand interactions. This review,follows the events of the functional cycle and discusses the findings in the context provided by the recently published x-ray structures. (C) 2003 Wiley Periodicals, Inc.

引用

页码：223 / 233

页数：11

共 57 条

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