Fe3O4 nanoparticles: a robust and magnetically recoverable catalyst for three-component coupling of aldehyde, alkyne and amine

被引:300
作者
Zeng, Tieqiang [1 ,2 ]
Chen, Wen-Wen [2 ]
Cirtiu, Ciprian M. [2 ]
Moores, Audrey [2 ]
Song, Gonghua [1 ]
Li, Chao-Jun [2 ]
机构
[1] E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Inst Pesticides & Pharmaceut, Shanghai 200237, Peoples R China
[2] McGill Univ, Dept Chem, Montreal, PQ H3A 2K6, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
HIGHLY ENANTIOSELECTIVE SYNTHESIS; C-H ACTIVATION; ONE-POT; TERMINAL ALKYNES; RUTHENIUM HYDROXIDE; EFFICIENT CATALYST; DIRECT-ADDITION; IRON-OXIDE; PROPARGYLAMINES; HYDROGENATION;
D O I
10.1039/b920000b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A robust, safe and magnetically recoverable Fe3O4 nanoparticle catalyzed three-component coupling of aldehyde, alkyne, and amine (A(3)-coupling) was developed. A diverse range of propargylamines were obtained in moderate to high yield under mild conditions in air. The separation and reuse of the magnetic Fe3O4 nanoparticles were very simple, effective and economical.
引用
收藏
页码:570 / 573
页数:4
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