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A pocket-sized convective PCR thermocycler

被引：66
作者：
Agrawal, Nitin
Hassan, Yassin A.
Ugaz, Victor M.
机构：
[1] Texas A&M Univ, Artie McFerrin Dept Chem Engn, College Stn, TX 77843 USA
[2] Texas A&M Univ, Dept Nucl Engn, College Stn, TX 77843 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 23期
关键词：
analytical methods; DNA replication; microreactors; molecular biology; polymerase chain reaction;
D O I：
10.1002/anie.200700306
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) Is that a PCR in your pocket? An innovative thermocycling system is presented that harnesses natural convection to perform rapid multiplex and long-target DNA amplification by the polymerase chain reaction (PCR). The design is inherently simple and consumes minimal electrical power, enabling a pocket-sized battery-powered device to be constructed at a cost of approximately US$10. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：4316 / 4319
页数：4
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