Enantioselective copper-catalyzed conjugate addition of dialkyl zinc to nitro-olefins

被引：94

作者：

Alexakis, A ^{[1
]}

Benhaim, C ^{[1
]}

机构：

[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 2, Switzerland

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 17期

关键词：

D O I：

10.1021/ol0059596

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The copper-catalyzed asymmetric conjugate addition of dialkylzinc onto various nitro-olefins has been carried out with excellent results, An enantiomeric excess of up to 94% was obtained using 0.5% Cu(OTf)(2) and 1% of chiral trivalent phosphorus ligand.

引用

页码：2579 / 2581

页数：3

共 22 条

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