Reversible and pH-Sensitive Vesicles from Amphiphilic Homopolymer Poly(2-(4-vinylphenyl)pyridine)

被引:57
作者
Changez, Mohammad [1 ]
Kang, Nam-Goo [1 ]
Lee, Chi H. [2 ]
Lee, Jae-Suk [1 ]
机构
[1] GIST, Dept Nanobio Mat & Elect, Dept Mat Sci & Engn, Kwangju 500712, South Korea
[2] Univ Missouri, Sch Pharm, Kansas City, MO 64110 USA
关键词
bilayers; homopolymers; pH sensitivity; vesicles; POLYMERSOMES; MICELLES;
D O I
10.1002/smll.200901670
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The sigma bond between the 2-phenyl pyridine head groups and the vinyl backbone of poly(2-(4-vinylphenyl)pyridine) allows for free rotation of the head groups in response to the polymer's environment and the hydrophobic vinyl backbone provides curvature for the formation of bilayer vesicles with a l-nm membrane thickness. The homopolymer vesicles act as a reservoir for both hydrophobic and hydrophllic molecules, individually or simultaneously. (Figure Presented). © 2010 WILEY-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:63 / 68
页数:6
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