Kinetic resolution for optically active epoxides by microbial enantioselective hydrolysis

被引：64

作者：

Choi, WJ

Huh, EC

Park, HJ

Lee, EY

Choi, CY ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Engn, Dept Chem Technol, Seoul 151742, South Korea

[2] Seoul Natl Univ, Coll Engn, Interdisciplinary Program Biochem Engn & Biotechn, Seoul 151742, South Korea

[3] Samsung Chem Grp, Seoul 100716, South Korea

来源：

BIOTECHNOLOGY TECHNIQUES | 1998年 / 12卷 / 03期

关键词：

D O I：

10.1023/A:1008825508904

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Resolution of several racemic epoxides was accomplished using an epoxide hydrolase activity of whole cells of the newly isolated Aspergillus niger. (S)-Styrene oxide, for example, was obtained from its racemates with optical purity of 100% ee and 32% yield.

引用

页码：225 / 228

页数：4

共 13 条

[1]

BROWN JH, 1991, TETRAHEDRON-ASYMMETR, V2, P481

[2] BIOFORMATION OF OPTICALLY PURE EPOXIDES [J].