Quinone approaches toward the synthesis of aflatoxin B2

被引:17
作者
Noland, WE [1 ]
Kedrowski, BL [1 ]
机构
[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA
关键词
D O I
10.1021/ol006014r
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Quinones bearing electron withdrawing groups can serve as useful precursors to furobenzofuran ring systems through their reaction with 2,3-dihydrofuran. Formal racemic and stereoselective syntheses of the fungal metabolite aflatoxin B-2 are described that utilize this approach to construct the tricyclic ABC-ring core of the molecule.
引用
收藏
页码:2109 / 2111
页数:3
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