Benzylsulfonyl: a valuable protecting and deactivating group in phenol chemistry

被引：6

作者：

Briot, A

Baehr, C

Brouillard, R

Wagner, A

Mioskowski, C

机构：

[1] Univ Strasbourg 1, UMR 7514 CNRS, Fac Pharm, Lab Synth Bioorgan, F-67400 Illkirch Graffenstaden, France

[2] Univ Strasbourg 1, UMR 7509 CNRS, Inst Bel,Fac Pharm, Lab Chim Polyphenols, F-67400 Illkirch Graffenstaden, France

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(02)02745-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

We introduce benzylsulfonyl (Bns) as a valuable protecting group in phenol chemistry. Bns proved to be stable under drastic reaction conditions and towards many common reagents. The deprotection proceeds quantitatively using catalytic hydrogenolysis. Additionally the Bns deactivating properties make this protecting group useful for tuning the reactivity of phenolic substrates. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：965 / 967

页数：3

共 11 条

[1]

A SYNTHESIS OF METHYL 3-O-(BETA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE FROM SULFONATE INTERMEDIATES [J].