Syntheses of hemoprotein models that can be covalently attached onto electrode surfaces by click chemistry

被引：49

作者：

Decreau, Richard A. ^{[1
]}

Collman, James P. ^{[1
]}

Yang, Ying ^{[1
]}

Yan, Yilong ^{[1
]}

Devaraj, Neal K. ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 72卷 / 08期

关键词：

D O I：

10.1021/jo062349w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Five alkyne-containing hemoprotein models have been synthesized in a convergent manner. Sonogashira coupling was used to introduce the alkyne functional group on the proximal imidazole before or after being attached on the porphyrin. One model was immobilized onto a gold electrode surface via copper(I)-catalyzed azide-alkyne cycloaddition (Sharpless click chemistry).

引用

收藏

页码：2794 / 2802

页数：9

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