Integration of a nanoporous platinum thin film into a microfluidic system for non-enzymatic electrochemical glucose sensing

被引：42

作者：

Joo, Segyeong

Park, Sejin

Chung, Thek Dong ^{[1
]}

Kim, Hee Chan

机构：

[1] Sungshin Womens Univ, Ctr NanoBio Appl Technol, Seoul 136742, South Korea

[2] Seoul Natl Univ, Interdisciplinary Program, Seoul 110744, South Korea

[3] Sungshin Womens Univ, Dept Chem, Seoul 136742, South Korea

[4] Seoul Natl Univ, Coll Med, Dept Biomed Engn, Seoul 110744, South Korea

[5] Seoul Natl Univ, Med Res Ctr, Inst Med & Biol Engn, Seoul 110744, South Korea

来源：

ANALYTICAL SCIENCES | 2007年 / 23卷 / 03期

关键词：

D O I：

10.2116/analsci.23.277

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this paper, we describe an amperometric-type enzymeless glucose sensing system based on a nanoporous platinum (Pt) electrode embedded in a microfluidic chip. This microchip system is comprised of a microfluidic transport channel network and a miniaturized electrochemical cell for nonenzymatic glucose sensing. Sample and buffer solutions were transferred to the cell by programmed electroosmotic flow (EOF). A nanoporous Pt electrode with the roughness factor of 200.6 was utilized to determine glucose concentrations in phosphate buffered saline (PBS) by the direct oxidation of glucose, without any separation process. The sensitivity of the developed system is 1.65 mu A cm(-2) mM(-1) in the glucose concentration range from 1 - 10 mM in PBS.

引用

页码：277 / 281

页数：5

共 23 条

[1] On chip single-cell separation and immobilization using optical tweezers and thermosensitive hydrogel [J].