Surface plasmon spectroscopic detection of Saxitoxin

被引：26

作者：

Chen, Hongxia

Kim, Youn Sook

Keum, Sam-Rok

Kim, Sung-Hoon

Choi, Heung-Jin

Lee, Jaebeom

An, Won Gun

Koh, Kwangnak ^{[1
]}

机构：

[1] Pusan Natl Univ, Coll Nanosci & Nanotechnol, Pusan 609735, South Korea

[2] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea

[3] Korea Univ, Coll Sci & Technol, Chungnam 339700, South Korea

[4] Kyungpook Natl Univ, Coll Engn, Taegu 702701, South Korea

来源：

SENSORS | 2007年 / 7卷 / 07期

关键词：

Saxitoxin; surface plasmon resonance; calixarene; self-assembled monolayer (SAM); COMPLEXATION; CHEMOSENSORS; RESONANCE; SODIUM; TOXINS;

D O I：

10.3390/s7071216

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

For the surface-optoelectronic study of Saxitoxin sensing, we fabricated self-assembled calix[4] arene derivative monolayers as the recognition-functional interfaces on a gold surface. An interaction study between Saxitoxin and calix[4] arene derivative monolayers were performed using surface plasmon resonance ( SPR) spectroscopy. Among three calix[4] arene derivatives, calix[4] arene crown ether SAM showed the highest sensitivity to Saxitoxin. The detection limit of this system is three orders of magnitude lower than that of the mouse bioassay which is the current benchmark for Saxitoxin detection.

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页码：1216 / 1223

页数：8

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