Direct electron detectors for electron microscopy

被引：14

作者：

Faruqi, A. R. ^{[1
]}

机构：

[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

来源：

ADVANCES IN IMAGING AND ELECTRON PHYSICS, VOL 145 | 2007年 / 145卷

基金：

英国工程与自然科学研究理事会; 英国医学研究理事会;

关键词：

D O I：

10.1016/S1076-5670(06)45002-3

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Some of the design principles and potential applications of direct-detection detectors for image recording and storage in electron microscopy (EM) are discussed. The major direct-detection detector technologies include hybrid pixel detectors (HPD) and monolithic active pixel sensors (MAPS). HPDs use separate pixellated detector and readout electronics chips and are able to acquire data without adding any noise. The design process of MAPS simplifies the design process and allows the integration of detector and readout on the same chip. Both detectors are based on the latest complementary metal oxide semiconductor (CMOS) design technologies, with significant potential to be used in EM applications. It is also found that the significance of direct-detection detectors have increased with growing application of EM for extensive data collection.

引用

收藏

页码：55 / 93

页数：39

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共 45 条

[11] Performance of a 2k CCD camera designed for electron crystallography at 400 kV [J].

Downing, KH ;

Hendrickson, FM .

ULTRAMICROSCOPY, 1999, 75 (04) :215-233

[12] Radiation damage studies on STAR250 CMOS sensor at 300keV for electron microscopy [J].

Faruqi, A. R. ;

Henderson, R. ;

Holmes, J. .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2006, 565 (01) :139-143

[13] Cooled CCD detector with tapered fibre optics for recording electron diffraction patterns [J].

Faruqi, AR ;

Henderson, R ;

Subramaniam, S .

ULTRAMICROSCOPY, 1999, 75 (04) :235-250

[14] Cooled CCD camera with tapered fibre optics for electron microscopy [J].

Faruqi, AR ;

Andrews, HN .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1997, 392 (1-3) :233-236

[15] CCD detectors in high-resolution biological electron microscopy [J].

Faruqi, AR ;

Subramaniam, S .

QUARTERLY REVIEWS OF BIOPHYSICS, 2000, 33 (01) :1-27

[16] Direct single electron detection with a CMOS detector for electron microscopy [J].

Faruqi, AR ;

Henderson, R ;

Pryddetch, M ;

Allport, P ;

Evans, A .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2005, 546 (1-2) :170-175

[17] Noiseless direct detection of electrons in Medipix2 for electron microscopy [J].

Faruqi, AR ;

Henderson, R ;

Tlustos, L .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2005, 546 (1-2) :160-163

[18] Evaluation of a hybrid pixel detector for electron microscopy [J].

Faruqi, AR ;

Cattermole, DM ;

Henderson, R ;

Mikulec, B ;

Raeburn, C .

ULTRAMICROSCOPY, 2003, 94 (3-4) :263-276

[19] Prospects for hybrid pixel detectors in electron microscopy [J].

Faruqi, AR .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2001, 466 (01) :146-154

[20] A multi-chip board for X-ray imaging in build-up technology [J].

Fornaini, A ;

Boerkamp, T ;

de Oliveira, R ;

Visschers, J .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2003, 509 (1-3) :206-212

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